DEAR READERS: With the development of herbicide-tolerant soybeans, corn and cotton in 1996, the use of glyphosate and glyphosate-based herbicides has increased dramatically -- and globally. It is also used as a pre-harvest desiccant on crops like wheat, barley, oats, soybeans, sorghum and beans to accelerate drying and make harvesting easier.
There is considerable published research on how this herbicide affects the nutritive value of treated crops by binding some essential nutrients such as calcium, manganese, magnesium, zinc and iron. Glyphosate is a chelating agent that has the potential to impact the uptake of lithium by binding to lithium ions. Low levels of lithium are associated with higher rates of depression, anxiety and insomnia; sensitivity to stress; chronic pain; and a decline in natural healing processes, memory and learning ability.
Glyphosate may also play a role in cardiovascular disease associated with low levels of magnesium. It reduces perinatal health and has been linked to metabolic dysfunction associated with fatty liver disease. Glyphosate can disrupt hormonal systems, leading to reduced fertility in animal tests. It has been linked to lower birth weights in humans, and has been implicated in neurobehavioral abnormalities in laboratory animal studies.
Glyphosate is thought to suppress cytochrome P450 enzymes, which play a crucial role in activating vitamin D within the liver and kidneys, converting it into its active form (calcitriol). Thus, inhibition of these enzymes could lead to impaired vitamin D activation and potentially deficiency. Glyphosate can disrupt the balance of bacteria in the gut (dysbiosis). A healthy gut microbiome is essential for various bodily functions, including nutrient absorption and immune system regulation. Some research suggests that alterations in gut bacteria might impact vitamin D metabolism or its effects on the immune system.
A 2023 analysis of several research studies of the carcinogenic potential of glyphosate states: “Our findings strengthen the mechanistic evidence that glyphosate is a probable human carcinogen and provide biological plausibility for previously reported cancer associations in humans, such as non-Hodgkin lymphoma.” (See the study "Mapping the key characteristics of carcinogens for glyphosate and its formulations: A systematic review" by Iemaan Rana et al., published in Chemosphere in 2023.)
It would therefore be advisable to consume USDA organically certified foods, since glyphosate is prohibited under organic standards, and organic soils are less nutrient-deficient than conventional. But recently, the USDA permitted hydroponic food producers to spray crops with glyphosate, putting their produce out of the "truly organic" category. (For more information, see realorganicproject.org.)
Feeding racehorses and breeding stock only organically certified dietary ingredients, or at least non-GMO feed tested for glyphosate, might help reduce racetrack deaths and injuries. Laminitis and gastric ulcer syndrome have also been associated with glyphosate-contaminated horse foods.
Glyphosate has been detected in high-fiber/high-cereal-content cat and dog foods. The prevalence of lymphoma and other cancers in companion animals, along with metabolic syndrome, intestinal dysbiosis and associated dermatological problems, may be related to this herbicide contaminant in their food.
Glyphosate contamination of streams and lakes allows toxic algae to proliferate, putting people and animals at risk. Homeowners and municipalities should cease and desist from using this herbicide to prevent runoff and environmental contamination.
For a deep dive into this and other products approved by the government, go to: midwesterndoctor.com/p/the-deadly-campaign-to-shield-all. And for supportive reference citations, see my post here: drfoxonehealth.com/post/farming-and-consuming-with-less-harm-and-the-the-glyphosate-saga.
(Send all mail to animaldocfox@gmail.com or to Dr. Michael Fox in care of Andrews McMeel Syndication, 1130 Walnut St., Kansas City, MO 64106. The volume of mail received prohibits personal replies, but questions and comments of general interest will be discussed in future columns.
Visit Dr. Fox’s website at DrFoxOneHealth.com.)